What is Credelio Plus 112,5 mg and which dogs is it indicated for?
Credelio® Plus 112,5 mg is a broad-spectrum oral chewable tablet specifically designed for dogs weighing between 2,5 and 5,5 kg. This antiparasitic combines the active ingredients lotilanate y milbemycin oximeoffering a complete solution against fleas, ticks, intestinal worms and serious parasites such as heartworm (dirofilariasis) and angiostrongylus (lungworm).
Formulated for easy administration thanks to its high palatability with a meat flavor, it is ideal for owners looking for simple but effective protection in a single monthly dose.
Composition and mechanism of action
Each Credelio Plus 112,5 mg tablet contains:
- Lotilaner: 112,5 mg
- Milbemycin oxime: 4,22 mg
El lotilanate It acts by blocking GABA- and glutamate-mediated chloride channels in ectoparasites (such as fleas and ticks), causing their paralysis and death. milbemycin oxime It interferes with neurotransmission in intestinal nematodes and dirofilaria larvae, acting on their nervous system to eliminate them effectively.
Veterinary indications
Credelio Plus 112,5 mg is indicated for the treatment and prevention in dogs weighing 2,5 to 5,5 kg that:
- They are infested with fleas (Ctenocephalides felis) and ticks (Rhipicephalus sanguineus, Ixodes spp.).
- They have or are at risk of contracting intestinal worms such as roundworms, hookworms y whipworms.
- They live in endemic areas of heartworm disease (heartworm) or angiostrongylosis (lung parasites).
- They require comprehensive monthly protection against internal and external parasites.
Administration method and usage guidelines
- Orally: administer 1 tablet per month.
- It should be given with food. or right afterwards to ensure proper absorption.
- The tablet should not be split, crushed, or dissolved.
Monthly administration ensures continuous protection against the main parasites of the dog.
Safety, precautions and side effects
Precautions:
- Do not administer to dogs with known hypersensitivity to the active ingredients.
- Consult your veterinarian if your dog has been in areas with a risk of heartworm disease before starting treatment.
- Caution in breeds with MDR1 (-/-) genetic mutation, such as the collie and its crosses.
- Safety in pregnant or lactating females has not been established. Use under veterinary supervision.
Rare side effects: Vomiting, diarrhea, loss of appetite, tremors, itching, or lethargy may occur. Rarely, mild neurological signs may appear, which usually resolve without treatment.
If adverse symptoms persist, it is recommended to consult a veterinarian immediately.
Advantages of Credelio Plus 112,5 mg
- Total protection against internal and external parasites in a single monthly tablet.
- Eliminates fleas and ticks in less than 4 hours.
- Effective treatment for intestinal worms, heartworm, and angiostrongylosis.
- Chewable tablet with high palatability.
- Ideal for dogs with active lifestyles or who travel frequently.
Frequently asked questions about Credelio Plus 112,5 mg for dogs weighing 2,5 to 5,5 kg
- How long does it take for Credelio Plus to take effect?
It starts eliminating fleas and ticks in less than 4 hours after oral administration. - Can I use Credelio Plus as a monthly preventative measure?
Yes, it is designed to be administered monthly to maintain continuous protection against internal and external parasites. - Is it safe for small puppies?
Yes, provided the puppy weighs at least 1,4 kg and is over 8 weeks old. - What happens if I miss a monthly dose?
Administer the dose as soon as you remember and resume the monthly schedule from that date. Consult your veterinarian if it has been a long time since the last dose. - Can it be administered together with other medications?
Yes, Credelio Plus has been shown to be safe when administered with other veterinary treatments. However, it is always recommended to consult your veterinarian before combining products. - Does Credelio Plus prevent heartworm?
Yes, its component milbemycin oxime is effective in preventing dirofilariasis (heartworm) with a monthly dose. - What differentiates Credelio Plus from other antiparasitics?
It combines action against internal and external parasites in a single dose, eliminating the need for multiple products. Furthermore, its pleasant taste makes it easy to administer.
Conclusion
Credelio® Plus 112,5 mg is the ideal solution for owners seeking comprehensive, convenient, and effective protection for small dogs. Its broad-spectrum formula, combined with its high palatability, makes it a reliable option for both treatment and long-term prevention.
One tablet a month protects your dog inside and out. Trust Credelio® Plus.

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