Composition and presentation
Felimazole 5mg/ml oral solution contains thiamazole (also known as methimazole) as the active ingredient at a concentration of 5 mg per milliliter. It is available in 100 ml bottles, accompanied by a dosing syringe to facilitate precise administration of the medication to cats with hyperthyroidism.
Therapeutic indications
Felimazole is indicated for the long-term treatment of feline hyperthyroidism, a common condition in older cats characterized by excessive production of thyroid hormones. This drug can also be used to stabilize the patient prior to thyroidectomy or radioactive iodine treatment.
Action mode
Thiamazole works by inhibiting the synthesis of thyroid hormones in the thyroid gland, specifically by blocking the iodination of tyrosine and the coupling of iodotyrosines. In this way, it reduces circulating levels of T3 and T4, helping to normalize the animal's metabolic parameters.
Advantages of the oral format
Felimazole's liquid formulation allows for more flexible dosing and easier administration in cats that have difficulty swallowing tablets. The included dosing syringe improves accuracy by adjusting the dose according to the cat's weight and clinical response.
Precautions and clinical follow-up
During treatment with Felimazole, regular monitoring of T4 levels, as well as blood counts and liver and kidney function tests, is recommended. This allows for evaluation of treatment efficacy and detection of potential adverse effects, such as leukopenia, hepatotoxicity, or signs of iatrogenic hypothyroidism.
Storage conditions
Felimazole should be stored at room temperature (between 15°C and 25°C), protected from direct light and out of the reach of children and untreated animals. Once opened, it is recommended to use the contents within a reasonable period following the manufacturer's instructions.
Frequently asked questions
- How long does it take for Felimazole 5mg/ml to take effect in cats with hyperthyroidism?
Generally, clinical effects begin to be observed between 1 and 3 weeks after the start of treatment, although complete normalization of T4 values may require dose adjustments and regular assessments. - In what cases is Felimazole oral solution preferred over tablets?
The liquid formulation is ideal for cats that refuse tablets or have difficulty swallowing, as well as for those that require meticulous adjustment of the daily dose. - Is Felimazole suitable for long-term use in geriatric cats?
Yes, provided that constant clinical monitoring is carried out. In many cases, the treatment is maintained for life with periodic adjustments. - What side effects may occur during the use of Felimazole 5mg/ml?
The most common adverse effects include vomiting, lethargy, anorexia, and hematological abnormalities. If persistent adverse signs occur, treatment should be reassessed. - Can Felimazole be administered along with other medications?
In most cases, yes. However, potential interactions with anticoagulants, nonsteroidal anti-inflammatory drugs (NSAIDs), and some antibiotics should be considered. Veterinary supervision is essential. - How is the dose of Felimazole oral solution adjusted?
The dose is individually adjusted based on the cat's weight and serum T4 levels. The dosing syringe allows for precise administration of doses in milliliters, facilitating adjustment. - What is the best way to administer Felimazole if the cat resists?
It can be mixed with a small amount of wet food or administered directly into the mouth with the syringe, making sure that the cat swallows it completely. - What veterinary checks are recommended during treatment with Felimazole?
It is suggested to perform blood tests every 2-3 weeks at the beginning and then every 3-6 months to monitor hormone levels and kidney and liver function.

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