Vetoryl 10mg 30 capsules |for chushing syndrome

VETORYL: Treatment of Hyperadrenocorticism in Dogs

VETORYL is a medication specifically formulated to control hyperadrenocorticism (Cushing's syndrome) in dogs. Its active ingredient, trilostane, acts by reducing the excessive production of glucocorticoids by the adrenal glands, helping to improve the quality of life of affected animals.

Presentations Available

• Vetoryl 10 mg: Trilostane 10 mg.
• Vetoryl 30 mg: Trilostane 30 mg.
• Vetoryl 60 mg: Trilostane 60 mg.

Excipients: Titanium dioxide (E171), yellow and black iron oxides (E172).

Therapeutic Indications

target species: Dogs.

• Treatment of hyperadrenocorticism of origin pituitary o adrenal.

Contraindications

1. Do not use in:
   • dogs with primary liver disease o renal insufficiency.
   • Animals weighing less than 10 kg.
2. Use in reproduction:
   • Contraindicated in bitches pregnant, lactating or intended for reproduction.

Adverse reactions

1. Corticosteroid Withdrawal Syndrome:
   • Differentiate it from the hypoadrenocorticism by evaluation of serum electrolytes.
2. Associated signs:
   • Lethargy, vomiting, diarrhea, anorexia.
   • Iatrogenic hypoadrenocorticism which may cause acute Addisonian crisis (collapse).
3. Isolated cases:
   • Adrenal necrosis that can lead to hypoadrenocorticism.
4. Other effects:
   • Ataxia, hypersalivation, abdominal swelling, muscle tremors, skin disorders.

If serious effects occur, discontinue treatment and contact your veterinarian.

Route of Administration

Orally.
Manage once a day, along with food.

Posology

1. Initial Dose:
   • 2 mg / kg daily. Adjust according to clinical response and monitoring.
2. Dosage Guide:
   • Give the lowest dose that controls symptoms.
   • In case of poorly controlled symptoms:
     • Increase up to a 50% of the daily dose.
     • Divide into two doses (morning and night).
   • Some dogs may require higher doses than 10mg/kg/day, with additional monitoring.
3. Important:
   • Do not open or divide the capsules.
   • Use combinations of capsule sizes to optimize dosage.

Special Precautions

1. Before Treatment:
   • Confirm accurate diagnosis of hyperadrenocorticism.
   • Rule out primary liver disease or renal failure.
2. During Treatment:
   • Monitor:
     • electrolytes, u, creatinine y liver enzymes.
     • dogs with d require special monitoring.
3. Specific Considerations:
   • Dogs previously treated with mitotane should wait a month before starting Vetoryl.
   • Caution in dogs with preexisting anemia due to possible reductions in blood cell volume.

Additional Risks

• Dogs with hyperadrenocorticism are at increased risk of developing pancreatitis, even during treatment.
• The drug may unmask subclinical renal dysfunction or arthritis.

Conservation Mode

• Temperature: Do not exceed the 25 ° C.
• Storage: Keep the capsules in their original blister inside the outer packaging.

Advantages of VETORYL

1. Effective Control: Relief of symptoms of Cushing's syndrome, improving the dog's well-being.
2. Custom Fit: Capsule combinations allow for precise dosing.
3. Easy Administration: It is administered once a day with food.
4. Wide Range of Use: Effective for both pituitary and adrenal hyperadrenocorticism.

FAQ

1. How long does it take to see improvement?
   Symptoms usually improve within the first few weeks of treatment.
2. Is regular monitoring necessary?
   Yes, regular testing is essential to adjust dosage and prevent complications.
3. Can it be used in combination treatments?
   Always consult your veterinarian before combining medications.
4. What to do if my dog ​​experiences serious side effects?
   Stop treatment immediately and contact your veterinarian.

Presentations and Registration

• Vetoryl 10 mg, 30 mg, 60 mg.
• Blister packs in secure packaging.

Medicine subject to a veterinary prescription. Consult your veterinarian to determine appropriate treatment.